The "three highs" of the wealthy diseases in modern society: hypertension, hyperglycemia, and hyperlipidemia, must be well known. But in recent years, the "fourth highest" - hyperuricemia has quietly appeared. And the "fourth highest" prevalence rate has even surpassed diabetes, with more than 1 in 10 people in mainland China suffering from the disease. According to statistics, the disease prefers male groups, with male and female prevalence rates of 19.4% and 7.9%, respectively. So what is hyperuricemia?

How high is uric acid to be considered hyperuricemia

Regardless of gender and age, check blood uric acid levels over 420 micromoles per liter on two separate days. It is a type of metabolic abnormal syndrome caused by disturbance of purine metabolism.

How does uric acid increase

Hyperuricemia is related to genetic factors, but in addition to genetic factors, the main reasons are: excessive uric acid production (eating too much purine-rich food, drinking alcohol, obesity, strenuous exercise, idiopathic rhabdomyolysis, etc.) or uric acid Decreased excretion (diabetes, hypertension, renal insufficiency, polycystic kidney disease, acidosis, etc.). Of course, there is also mixed hyperuricemia in which both conditions coexist.

Harm of high uric acid

Continued increase in serum uric acid will cause the following hazards: when deposited in the kidneys, it will cause kidney damage, urinary tract stones, and gouty nephropathy; uric acid deposition in the joints will cause gouty arthritis, which can lead to joint destruction and deformation; high uric acid can also stimulate the blood vessel wall , promote atherosclerosis; damage pancreatic β cells and then cause insulin resistance and aggravate diabetic metabolic syndrome.

Keep your mouth shut, can you control high uric acid?

The answer is not entirely correct. Strict diet control can only reduce blood uric acid by 60 to 120 micromoles per liter, because 20% of uric acid in the body comes from diet and 80% from cell metabolism. At the same time, long-term strict diet control may lead to malnutrition. Therefore, it is necessary to seek medical attention in time and use drug treatment to reduce uric acid levels.

What checks should be done in patients with hyperuricemia

Check accordingly under the guidance of a doctor. Relevant checks may include:

1. Blood test: uric acid, serum creatinine, blood lipids, blood sugar, serum creatinine;

2. Urine examination: uric acid, urine PH value;

3. Dual-source CT examination: check whether there is urate crystal deposition in the joints;

4. B-ultrasound: check whether there are stones in the urinary system;

5. X-ray examination: check for bone destruction;

6. Joint fluid examination: check to identify crystals and inflammation;

7. Histological examination: urate crystals.

High uric acid, can I still drink alcohol

Drinking alcohol is not recommended, especially during acute gout attacks and chronic gouty arthritis. During the intermittent period of gout, the blood uric acid level reaches the standard, and drinking can be controlled.

What are the key points of diet

Limit the intake of purines, and control the daily dietary purine content to less than 200 mg.

Encouraged foods include 500 grams of fresh vegetables per day, 1 egg per day, skim or low-fat milk (300 ml per day), and low-glycemic index cereals. At the same time, except for patients without heart and kidney disease, it is recommended to drink more water, drink 2 to 3 liters of water a day, and try to use weakly alkaline and small molecular water for drinking water. Dietary adjustment should run through the disease from beginning to end.

Through the above knowledge of hyperuricemia, I hope that we will take care of ourselves, live a healthy life, and reject high uric acid.