Are men more likely to get cancer than women?

2022-09-09

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Why do men have higher cancer risk than women?

Are men really more prone to cancer than women? The data already speaks for itself.

The results of the China Cancer Burden Survey show that the incidence and mortality of the top ten malignant cancers in males and females are at least half of which are much higher than those of females , and the other half are basically the same or slightly higher for women.

According to a statistical survey in the United Kingdom, the risk of cancer among men is 16% higher than that of women, and the risk of cancer death exceeds 40%;

In 2017, the American Cancer Statistics Survey data pointed out that the risk of cancer in men is 20% higher than that of women, and the risk of cancer death is 40% higher.

The Global Situation Survey tells people the truth: excludes sex-related cancers , The risk of all other cancers in men is 20% higher than in women, and the mortality rate is nearly twice that of women. The high incidence of cancer in men may be related to the following reasons.

1. Gene differences

In addition to the above UTX and UTY, the common genes associated with human cancer are TP53 and SRY genes. Studies have found that At least one-half of all known cancers in humans will affect the expression of the TP53 gene , and this gene is precisely the "natural protective barrier" of human genes.

In-depth research found that TP53 is concentrated on the X chromosome, and is not easily mutated in females , on the contrary, the risk of mutation in males is extremely high. That is to say, the genetic protection of men is not as good as that of women. Once a genetic mutation occurs, men are also more vulnerable to genetic abnormalities.

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2. Differences in living habits

A survey by the Chinese Academy of Medical Sciences and the American Cancer Society found that alcoholism, smoking, overweight, nutritional imbalance, lack of exercise and other factors contributed to 50% of cancer deaths in China in 2013. The correlation was only one-third among women who died.

This is closely related to the difference in sexual habits between men and women. In fact, men are more likely to smoke, drink alcohol, be overweight, and have nutritional imbalances.

Smoking: China The smoking rate of adult males is as high as 52.9%, which is close to 300 million people, while only 2.7% of females . Studies have found that when tobacco is burned, more than 7,000 compounds are released, of which alone are known to cause as many as 69 kinds of substances that cause cancer , and smoking causes cancer is also a clinical problem. major risk factor.

Alcoholism: The vast majority of drinkers are men, but compared with smoking, the number of women drinking has also increased rapidly in recent years. Alcohol can stimulate and damage the human body and increase the possibility of cancer.

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3. Differences in personality and pressure

Men suffer from stronger competition in society and groups. Coupled with the endocrine differences between men and women, men are also more easily excited and impulsive in character. All kinds of situations have contributed to the phenomenon of men's huge survival pressure. The adverse effects of personality and stress can directly or indirectly increase the risk of cancer in men.

4. Differences in immunity

The study found that women's innate immunity and acquired immunity are higher than men's , and taking acute HIV infection as an example, women's blood viral load is often 40% lower than that of men, which may be related to gender differences at the onset of the disease, Differences in genetic material between men and women, reproductive characteristics of men, etc. are related.

In short, women's immunity is higher than that of men, and their resistance to cancer is naturally higher than that of men.

5. Age difference

During the entire life cycle, the bodies of men and women are changing at any time. cells, endocrine and structure will also undergo several complete changes, which will also cause differences and contrasts in immunity between men and women. , so at different ages, men and women have different risk and cancer risk.

In addition to the above factors, multiple factors such as nutrition, fertility, environment, radiation, and exposure to dangerous substances may also bring cancer risks to the human body. These are also important factors in cancer prevention. comprehensive consideration.

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